NQAD – See what others can’t

The ultra-sensitive, universal NQAD TM presents a major advancement in high performance liquid chromatography detection capability.

The NQAD line of detectors for HPLC, UHPLC and SFC separations measure semi-volatile and nonvolatile analytes. The unique NQAD sees what others can’t!

Compared to conventional aerosol based detectors, only the NQAD incorporates patented Water Condensation Particle Counting (WCPC) technology which improves sensitivity, linearity, stability, and precision. It is truly a new and completely different kind of aerosol-based detector for HPLC. (WCPC technology is well-known and widely used in other scientific fields with an excellent track record in climate research and nanoparticle technology.)

Compared to other aerosol-based detectors, the NQAD shows less baseline drift and background detector noise whilst offering superior sensitivity for most analytes.

The unique NQAD combine the versatility and performance required for analytical R&D with the reproducibility needed for QA/QC. The stability and ruggedness combines with the small footprint making the detectors ideal for any testing in a demanding lab environment. They can be used for virtually any compound, industry or application, as noted in Drug Discovery & Development (2010).

Typical compounds include: drug compounds, proteins, polymers, peptides, lipids, steroids, carbohydrates, ions

Typical applications include: impurity analysis, method transfer, excipient characterization, degradation product analysis, cleaning validations, academic research, detecting compounds that lack a chromophore

Typical industries include: pharmaceuticals, industrial chemicals, specialty chemicals, food and beverage, nutriceutical, life sciences, agricultural chemicals, biofuels

The NQAD line of detectors measures analytes that do not contain a chromosphere or fluorophore without the need for cumbersome derivatization steps. Direct detection of compounds that are not good UV absorbers saves a significant amount of time and expense.

Compact Size Yet Robust and Reliable: QT-500 Model NQAD

Dimensions: 7” x 17” x 12.5”, yet robust and reliable.
Weight: 25 lbs. The NQAD Detector is easy to set up and operate.
Power requirements: 150 Watts, 100-240 VAC, 50-60 Hz.
Product safety/compliance: CE certification based on 80/336/EEC, EN55011, EN61326-1, EN61010-1.

The unrivaled performance of the Quant Technologies NQAD Detectors truly makes this all in one detector, the one for all.

Compact Size Yet Robust and Reliable: QT-600 Model NQAD

Dimensions: 6” x 1” 9x 12.9”, yet robust and reliable
Weight: 24 lbs. The NQAD Detector is easy to set up and operate
Power requirements: 150 Watts, 100-240 VAC, 50-60 Hz.
Product safety/compliance: CE certification based on 80/336/EEC, EN55011, EN61326-1, EN61010-1.

The NQAD line of detectors combines the versatility and performance required for analytical R&D with the reproducibility needed for QA/QC.

Model Feature Comparison

QT-500 Model NQAD QT-600 Model NQAD
Excellent sensitivity (typically ng on-column) Excellent sensitivity (typically ng on-column)
Unrivaled precision (<2% RSD’s typical) even at low concentrations Unrivaled precision (<2% RSD’s typical) even at low concentrations
Wide linear range (typically four orders of magnitude) Wide linear range (typically four orders of magnitude)
Broad applicability and versatility Broad applicability and versatility
Simple operation Simple operation
  Ability to detect semivolatile analytes [cooled evaporator in the QT-600]
  Optimized for SFC [heated nebulizer in the QT-600]
  Optimized for UHPLC [100 Hz sampling rate]
Suitable for most UHPLC (50 Hz sampling Optimized (100 Hz sampling rate) for the fastest UHPLC applications with sub-second eluting peaks

Key benefits:

  • Increased productivity
    • Detect more compounds per injection (high and low concentration)
    • Reduced mathematical manipulation of data
    • Long term stability and robustness
  • Minimal cost
    • One detector can be used for UHPLC, HPLC, and SFC
    • Minimizes organic solvent purchase and disposal costs
    • Few expendables – the wick costs under $100
    • Operates on air or nitrogen.

Instrumentation